Isa is the Arabic form of Jesus, the name of the prophet in the Quran, and ultimately goes back to the Hebrew Yeshua, "God saves" or "God is salvation". In Spanish and German-speaking countries Isa is also a girls' short form of Isabel or Isabella, but in the United States it is more often given to boys from Muslim families. Isa climbed from number 2644 in 2000 to number 933 among boys' names in 2025, its first year in the top 1000.