Kayne is a spelling of Kane, an Irish surname from Ó Catháin, a name built on the Irish cath, "battle", so it is read as "little battler". Its peak in the late 2000s coincided with the fame of Kanye West, whose name many hear in it, and the y spelling also recalls Wayne and Zayne. Kayne ranked number 2108 in 2000, reached number 1418 in 2008 and has slipped to number 2666 in 2025 with 49 boys.