Isael is used mainly in Spanish-speaking families and is of uncertain origin, usually explained as a variant of Israel, the biblical name read as "he struggles with God", or as a shortening of Ismael. It shares the gentle -el ending of Uriel and Misael. In the United States Isael climbed from number 1939 in 2015 into the top 1000 in 2024 and ranks number 989 in 2025.