Weslee is a modern spelling of Wesley, an English surname and place name meaning "western meadow", from Old English west and leah. Wesley became a first name in honor of John Wesley, the 18th century founder of Methodism, and Weslee gives it a casual, phonetic look. In the United States Weslee ranked number 4060 in 2000, peaked at number 2507 in 2023 and was given to 51 boys in 2025, placing it at number 2600.