Roxanna is a form of Roxana, the Greek rendering of the Persian Roshanak, which means "bright" or "dawn". Roxana was the Bactrian princess who married Alexander the Great, and the name later spread through Europe in the Latin spelling Roxana and the French Roxane. In the United States Roxanna is used mainly in Hispanic families; it peaked at number 1276 in 2001 and stands at number 2856 in 2025.