Maysen is a girls' spelling of Mason, an English occupational surname for a "stoneworker" or "bricklayer", from the Old French masson. The -sen ending marks it as feminine in the same way as Madisyn and Emersyn, and the May- opening calls up the month and the name May. Maysen stood at number 5860 in 2000 and stayed rare for two decades before jumping from number 7519 in 2023 to number 2526 in 2025, its best rank so far.