Margo is a phonetic spelling of Margot, the French short form of Marguerite, which goes back to the Greek margarites and means "pearl". Actress Margo Martindale and the character Margo Channing in the film All About Eve give it a classic Hollywood air. In the United States Margo re-entered the top 1000 in 2018 after decades away and ranks number 559 among girls' names in 2025.