Gregorio is the Spanish and Italian form of Gregory, from the Greek Gregorios, which means "watchful" or "alert". Sixteen popes have carried the name, among them Gregory the Great, and the Baroque composer Gregorio Allegri wrote the famous Miserere. In the United States Gregorio stood at number 1049 in 2000, slipped to number 1989 by 2015 and ranks number 2336 among boys' names in 2025.