Gisselle is a spelling of Giselle, a French name from the Germanic gisil, which means "pledge" or "hostage", recalling the medieval custom of sending noble children to another court as a guarantee of peace. The Romantic ballet Giselle made it a dancer's name, and the double s spelling is favored in Spanish-speaking families. Gisselle ranked number 367 in 2000, its best year in the data, was number 1299 in 2015 and ranks 1812 in 2025.