Lilyana is a modern blend of Lily and Liliana, so it carries the meaning "lily", the flower that has stood for purity since the Middle Ages; Liliana is itself the Spanish and Italian form of Lillian. The Y spelling appeared in the United States in the 2000s, when Lily and Liliana were both climbing. Lilyana entered the top 1000 in 2006, peaked at number 472 in 2011 and ranks number 1050 in 2025.