Jaysen is a modern spelling of Jason, from the Greek Iason, which comes from iasthai, to heal, and means "healer". The leader of the Argonauts gave the name its mythological pedigree, and Jason was a top 10 name in the 1970s; the -sen spelling gives the familiar name a fresh look, parallel to Jaycen and Jayceon. Jaysen stood at number 1732 in 2000, peaked at number 1390 in 2011 and ranks 1830 among boys' names in 2025.